GHK-Cu + Tirzepatide

Ghk Cu + Tirzepatide

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19

authors mention this stack

17

ran the components concurrently

GHK-Cu + Tirzepatide (GHK-Cu + Tirzepatide) appears in 19 author journeys (17 as actual concurrent use). Common goals: Weight loss, skin health, and general wellness; Tirzepatide for weight loss and weight maintenance; GHK-Cu to improve physical appearance/skin for an upcoming wedding.; Weight loss and transition support (specifically skin and hair improvement). Typical doses reported: Tirzepatide 7.5mg, GHK-Cu 1.5mg. Reported side effects include: Severe stinging sensation from GHK-Cu (described as feeling 'stung by a hornet/wasp')

Typical doses reported

Tirzepatide 7.5mg
Ghk Cu 1.5mg

Community-reported doses are not medical guidance.

How people are running it

16

Currently running

2

Planning to run

1

Ran in the past

1

Recommended / discussed

What people use it for

Weight loss, skin health, and general wellnessTirzepatide for weight loss and weight maintenance; GHK-Cu to improve physical appearance/skin for an upcoming wedding.Weight loss and transition support (specifically skin and hair improvement)Weight maintenanceWeight loss, appetite suppression (Tirzepatide); hair/skin health, avoiding loose skin from weight loss, inflammation (GHK-Cu)Weight loss (Tirzepatide) and preventing skin laxity (GHK-Cu)

Sample reported outcomes

  • ✓ Weight loss progress (down 21 lbs as of mid-September)
  • ✓ Maintained weight loss, hovering between 125-130 lbs. The effectiveness of GHK-Cu on appearance was too early to tell as of January 2026.
  • ✓ No injection site reactions or typical post-injection stinging from GHK-Cu
  • ✓ 29 lbs down (as of May 8, 2026), skin seems more plump, A1C decreased by 1.5%, thyroid levels improving.
  • ✓ Successful slow weight loss with Tirzepatide; continued use of GHK-Cu at a lower dose
  • ✓ Noticed better skin on face and body, though no change in under-eye appearance.
  • ✓ Consistently losing 1-2kg per week, went from 100kg to 90kg between February and April 2026
  • ✓ DSIP has significantly improved sleep quality, showing increased deep/REM sleep and less awake time on tracker

Self-reported community experiences, not verified results.

Sample reported side effects

  • ⚠ Severe stinging sensation from GHK-Cu (described as feeling 'stung by a hornet/wasp')
  • ⚠ GHK-Cu caused a severe injection site sting initially, which subsided over time. Tirzepatide caused constipation and general gastric issues.
  • ⚠ None
  • ⚠ Injection site reactions (ISR) from GHK-Cu including stinging, redness, and hard, itchy welts (which improved with dilution and over time).
  • ⚠ Severe headache, nausea, and extreme fatigue/somnolence the morning after taking 15 units of GHK-Cu
  • ⚠ Apprehensive about the expected injection sting.
  • ⚠ Injection sting from GHK-Cu
  • ⚠ anhedonia (from Tirzepatide)