Ipamorelin + Retatrutide + Tesamorelin

Ipamorelin + Retatrutide + Tesamorelin

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27

authors mention this stack

13

ran the components concurrently

Ipamorelin + Retatrutide + Tesamorelin (Ipamorelin + Retatrutide + Tesamorelin) appears in 27 author journeys (13 as actual concurrent use). Common goals: weight loss and body composition; Mitochondrial repair, sleep optimization, mood enhancement, cognitive focus, and weight loss.; maintain muscle mass and improve sleep quality. Typical doses reported: Ipamorelin 250mcg, Retatrutide 2mg, Tesamorelin 1mg. Reported side effects include: Larger nighttime doses of Tesamorelin (1-1.5mg) caused sleep disruption. Retatrutide at 5mg was too high of a dose.

Typical doses reported

Ipamorelin 250mcg
Retatrutide 2mg
Tesamorelin 1mg

Community-reported doses are not medical guidance.

How people are running it

10

Ran in the past

9

Planning to run

6

Recommended / discussed

4

Currently running

What people use it for

weight loss and body compositionMitochondrial repair, sleep optimization, mood enhancement, cognitive focus, and weight loss.maintain muscle mass and improve sleep qualityTo focus on targeting midsection/belly fat while transitioning or lowering Retatrutide dosageweight loss and sleep improvementWeight loss and body recomposition

Sample reported outcomes

  • ✓ Excellent sleep at the specified nighttime doses (.5mg Tesamorelin + 150-200mcg Ipamorelin), significantly improved mood and mental focus from daytime Tesamorelin, and lost approximately 35 pounds alongside reduced systemic inflammation (attributed to Retatrutide).
  • ✓ Worsened sleep, leading the author to discontinue Ipamorelin
  • ✓ Weight loss flatlined/stalled around 280 lbs after an initial 9 lb weight gain during Christmas week, though body composition felt slightly improved.
  • ✓ Net weight loss of zero in the first week, likely due to water retention
  • ✓ Substantial muscle growth ('totally jacked'), rapid recovery from daily heavy lifting, weight reduction returning after initial water weight gain, high energy levels
  • ✓ No outcomes yet (planned stack).
  • ✓ Unspecified reaction ('this happened instantly')
  • ✓ The Retatrutide turned milky white almost immediately upon mixing, so the author did not inject it.

Self-reported community experiences, not verified results.

Sample reported side effects

  • ⚠ Larger nighttime doses of Tesamorelin (1-1.5mg) caused sleep disruption. Retatrutide at 5mg was too high of a dose.
  • ⚠ slight decrease in quality of sleep from Retatrutide
  • ⚠ Kept the author awake at night
  • ⚠ Increased food noise compared to early Retatrutide use, unease/nausea after consuming alcohol or sugar.
  • ⚠ Water weight retention
  • ⚠ Elevated blood pressure, elevated resting heart rate, and low ferritin levels (20.3 ng/mL)
  • ⚠ No side effects yet (planned stack).
  • ⚠ Unspecified reaction ('this happened instantly')