Selank

Cognitive Research Compound

Synthetic tuftsin analog peptide

Mechanism of Action

Heptapeptide analog of tuftsin with reported anxiolytic and immunomodulatory effects, possibly via GABA/serotonin and BDNF modulation.

Note: Prescription anxiolytic in Russia; research-only elsewhere

954

Community Posts

281

Users Discussing

4

Research Articles

1

Clinical Trials

Reported Outcomes

Clinical grade reflects published research; Community grade reflects user reports (n=954).

Outcome

Clinical

Community

Reported by

Mental/Mood

Effects on mood and cognitive function

Clinical: D

Community: B

31% (149)

Sleep Quality

Effects on sleep quality

Clinical: D

Community: B

28% (156)

Energy Levels

Changes in energy and fatigue levels

Clinical: D

Community: B

14% (60)

Who Discusses Selank

From community reports with demographic data.

Gender (limited data)

Male 69%

Female 31%

n=35

Age Distribution (limited data)

50.5

median age

range: 23-75

<30

30s

40s

50s

60+

n=12

Side Effects

Based on 51 user reports (n=51). Frequency indicates how often each was mentioned.

Common (>5%)

Constipation

Mild 4 reports 7.1%

Hair Loss

Mild 4 reports 7.1%

Nausea

Mild 4 reports 7.1%

Water Retention

Mild 4 reports 7.1%

Injection Site Reaction (Isr)

Mild 3 reports 5.4%

Fatigue

Mild 3 reports 5.4%

Insomnia

Mild 3 reports 5.4%

Uncommon (1-5%)

Syncope

Mild 2 reports 3.6%

Extreme Appetite Suppression

Mild 2 reports 3.6%

Ipamorelin)

Mild 2 reports 3.6%

Increased Hunger

Mild 2 reports 3.6%

Elevated Heart Rate

Mild 2 reports 3.6%

Ibs-C

Mild 1 reports 1.8%

Hypoglycemia

Mild 1 reports 1.8%

Risks & Warnings

Important safety considerations based on clinical data and community reports.

!

Psychiatric Effects

11 mentions

Monitor for mood changes. Report any concerning psychiatric symptoms to healthcare provider.

i

Injection Site Reactions

10 mentions

Local reactions are common and usually mild. Rotate injection sites.

Dosing

Standard Protocol

Starting Dose: 250-900mcg daily intranasal (community protocols)
Titration: No established protocol
Half-life: Short
Administration: Intranasal or subcutaneous

Community Dosing Patterns

Based on 55 mentions

Community-reported patterns, not medical advice.

daily

9

500mcg daily

4

300mcg daily

3

1mg daily

2

500mcg

2

Research

4

Total Articles

1

Clinical Trials

1

Reviews

Key Studies

Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. Review

J Am Acad Orthop Surg Glob Res Rev (2026)

Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission Preclinical

Frontiers in Pharmacology (2016)

Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats Preclinical

Behavioural Neurology (2017)

GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells Preclinical

Front Pharmacol (2017)

Commonly Stacked With

From community members' documented stacks involving Selank.

Semax 73 stacks (73%)

Tirzepatide 21 stacks (21%)

MOTS-c 15 stacks (15%)

Retatrutide 15 stacks (15%)

GHK-Cu 15 stacks (15%)

Switching Patterns

Based on 60 discussions about switching to or from Selank.

→ Switching FROM

Semax 12 mentions

Retatrutide 8 mentions

Epitalon 8 mentions

GHK-Cu 4 mentions

Users who switched to Selank

← Switching TO

Semax 14 mentions

MOTS-c 6 mentions

GHK-Cu 5 mentions

SS-31 5 mentions

Users who switched from Selank